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 View a collection of supplementary multimedia files contributed by our authors/editors related to their published Artech House titles in Bioengineering, Bioimaging and Bioinformatics.
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 Read about our Bioengineering, Bioimaging and Bioinformatics series descriptions and series editors, or get detailed information for prospective new Artech House authors.
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Book Abstract:
Adaptive microwave phased array antennas are well known for their ability to improve the performance of communications and radar systems. And now, adaptive phased array techniques are beginning to be successfully applied to RF and microwave thermotherapy treatment of cancerous tumors. This groundbreaking book details innovative phased array techniques currently being developed at the MIT Lincoln Laboratory for cancer treatment. Until now, this material has only been available in Lincoln Laboratory reports and peer-reviewed journals.
From electromagnetic field theory for tissue heating… to simulations of adaptive phased array thermotherapy for deep tumors of the torso… to coverage of arrays for tumors in the head, neck, breast, and chest wall, this timely resource offers you expert guidance in this emerging area. You also find an insightful look at future research topics for adaptive phased array thermotherapy.
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Book Abstract:
Ranging from basic principles to advanced concepts and real-world applications, this comprehensive reference offers you expert guidance in radiation dosimetry. The book thoroughly examines the physics of radiation, its biological effects, commercial products, device design, and measurement methods. You find critical details on sensing using thin/thick film technology and discover the latest about gamma radiation dosimetry using metal oxides and polymers, including metal substituted phthalocyanines.
You gain deep knowledge of the effects of radiation on physical processes, helping you to design more cost-effective dosimeter devices. The book presents in-depth information on commercially available dosimetry equipment, offering you a solid understanding of how these products operate and how to use them in mining, construction, medical, energy, defense, and security applications. In addition, this cutting-edge volume presents the radiation dose concept, where accuracy of dose measurement and classification between different radiation types, e.g. alpha, beta, gamma etc, is enhanced by applying specific pattern recognition algorithm.
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Book Abstract:
This cutting-edge resource provides you with a practical and theoretical understanding of state-of-the-art techniques for electrocardiogram (ECG) data analysis. Placing an emphasis on the fundamentals of signal etiology, acquisition, data selection, and testing, this comprehensive volume presents guidelines to help you design, implement, and evaluate algorithms used for the analysis of ECG and related data. Additionally, explanations of open source software and related databases for signal processing are given.
The book focuses on the modeling, classification, and interpretation of features derived from advanced signal processing and artificial intelligence techniques. Key topics covered include physiological origin, hardware acquisition and filtering, time-frequency quantification of the ECG and derived signals (including heart rate variability and respiration), analysis of noise and artifact, models for ECG and RR interval processes, linear and nonlinear filtering techniques, and adaptive algorithms such as neural networks.
Much of the book is devoted to deriving robust, clinically meaningful parameters such as the QRS axis, QT-interval, the ST-level, and T-wave alternan metrics. Methods for applying these metrics to clinical classification are also discussed, together with supervised and unsupervised classification techniques. Including over 190 illustrations, the book offers you a solid grounding in the relevant basics of physiology, data acquisition and database design, and addresses the practical issues of improving existing data analysis methods and developing new applications.
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Book Abstract:
Here’s the first state-of-the-art design reference on artificial implant surfaces. It takes you to the cutting-edge of efforts to understand and control the constant interactions taking place between biomaterials and biological media. The book explores processes and surface modifications that occur in various bio/non bio interfaces, and provides the latest performance-enhancing design, materials selection, and manufacturing guidance—including nanotechnology breakthroughs that are ushering in a new age of biomaterial design and applications.
After an extensive discussion of biomedical surfaces attributes, the book addresses design issues that arise where materials and biofluids interface and the suppression or selective adsorption of biomacromolecules is a key objective. Implant lubrication and wear issues are covered, including adsorption of lubricants on surfaces and the tribology of the surfaces themselves. The book explores interaction issues crucial to predicting biomaterial interactions with body tissues, including protein adsorption and desorption processes, immune cell response, the assimilation and interaction of cells like osteocytes, and bacterial infection risks, and includes a chapter on biomedical surfaces manufacturing which emphasizes practical design issues. The volume also examines emerging nano-engineered materials including “smart” surfaces that are responsive to host cells and tissues, as well as novel drug delivery surfaces developed with nano- and microtechnologies. Complete with techniques for measuring surface properties, this well-illustrated resource helps you design or select implants that deliver ever-higher levels of performance and durability.
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Book Abstract:
Gain thorough understanding of the science and engineering behind today’s most advanced life sciences automation devices, systems, and technologies and their applications in biotechnology, pharmacology, and healthcare with this cutting-edge book. This comprehensive interdisciplinary resource details state-of-the-art design, modeling, and fabrication techniques for automation tools and demonstrates how they can be most effectively integrated in powerful medium-scale to large-scale automation systems to solve specific problems and challenges in the biological sciences.
Showcasing the world’s top researchers in the field, this definitive work brings you up to speed with basic molecular biology, analytical chemistry, and healthcare delivery methods together with engineering principles at the heart of human-machine interactions, machine vision, robotics, and control theory. It explores the latest advances in the design and development of sensors and actuators, lab-on-a-chip and bio-MEMs platforms, DNA and protein microarray fabrication automation, and drug delivery automation, and details how these devices perform in a broad range of system-level applications, including AFM-based systems as well as bio-instrumentation, cell and tissue manipulation, and laboratory automation. The book also spotlights emerging nanotechnology applications as well as genomics, proteomics, and pharmacogenomic automations. Supported by a wealth of real-world examples and 114 illustrations and photos, this indispensable work delivers breakthrough applied research and R & D technology that will help you successfully use life science automation and develop new applications and capabilities in the field.
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Book Abstract:
Helping to bridge the gap between medicine and engineering, this groundbreaking resource provides a detailed understanding of the analysis, design, and application of new intelligent systems in the biomedical industry. The book covers the three major areas of application in biomedicine, including the modeling and control in human anaesthesia, decision support for critically ill patients in intensive care units, and modeling of humans who are subjected to physical workload stress.
You'll find expert guidance on signal processing in Anaesthesia; systems modeling and feedback adaptive control of Anaesthesia; model reduction of physiological modeling using systems engineering; design of intelligent-systems-based decision support systems in critical and life-threatening environments; and hybrid modeling – combining intelligent systems structures with physical models. This cutting-edge reference also describes the monitoring and closed-loop control of anaesthesia via blood pressure measurements during surgery. Additionally, you learn a new systems engineering approach to the modeling of human physiology via pharmacokinetics/pharmacodynamics studies relating to anaesthetic drugs.
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Book Abstract:
This definitive work provides an innovative methodology for biomedical signal analysis. It helps bridge the gap from visual analysis of EEGs to advanced signal processing techniques, serving as the first clear guide to adaptive approximations and the matching pursuit (MP) algorithm. You find a review of signal processing essentials, written in plain English, from sampling of analog signals and the inner product, to spectral and time-frequency methods of signal analysis.
This groundbreaking book introduces adaptive approximations and the basics of the matching pursuit algorithm, and explains advantages and limitations in applications relying on EEG analysis. From the parameterization of EEG transients to selective estimates of energy of relevant structures, various applications in sleep, ERD/ERS, pharmaco-EEG, and epilepsy research are explained, each spotlighting a unique feature of the matching pursuit algorithm. This comprehensive resource provides full mathematical details for all applications, including tricks necessary for efficient MP implementation, to help you modify procedures as needed or design all-new frameworks for analysis of biomedical signals. Moreover, software used in the applications can be downloaded free from the author’s website.
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Book Abstract:
This single authoritative volume takes bio-device research and development to the next level, covering the latest advances in biomedical micro-electro-mechanical systems (MEMS) and nano-electro-mechanical systems (NEMS). This applications-focused book covers everything from fundamental mechanics of microactuators, to the most recent breakthroughs in the bio-manipulation and actuation of cells and genes.
This trail-blazing work brings you up to speed on the synthesis and use of metallic nanoparticles in bio-sensing and drug delivery applications, including quantum dots-semiconductors nanocrystals-with their unique electronic and optical properties. It then explores the latest advances in micro and nano manipulation techniques, including manipulators and endoscopes for microsurgery, nano-based optical in-vitro and in-vivo imaging diagnostics, targeted delivery and guided therapy, optical trapping of subcellular components, and optical nano-surgery of subcellular components. Coverage also includes dielectrophoretic methods for biomedical applications, as well as hardware, software, and control issues involved with micro and nano precision robotic systems for cell manipulations and injections. A final section explores state-of-the-art dynamic modeling and analysis for gene manipulations. Showcasing the work of leading international experts and exhaustively referenced, this comprehensive and far-reaching volume helps you achieve greater success in the manipulation, control, modeling, and simulation of bio-devices at the micro and nano scale.
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Book Abstract:
This groundbreaking work puts you at the cutting edge of diagnostic and therapeutic bioengineering, and brings you up to speed with the extraordinary range of cell-based biomedical applications now in development. Written by pioneers in the field, it explores the top-down and bottom-up technologies that can be used to control various aspects of the stem cell microenvironment. The book shows how these microfabrication and material synthesis techniques are paving the way to dramatic clinical breakthroughs in areas ranging from in vitro fertilization to artificial skin and organ tissue generation.
Supported with 140 illustrations, the volume exhaustively covers the micro- and nano-system technologies involved in developing cell-based bioengineering applications. You get full details on efforts to engineer the soluble and insoluble cell microenvironments, including the latest advances in microfluidic devices, surface patterning, 3D scaffolds, and techniques for engineering cellular mechanical properties and topography. The book systematically reviews emerging biomedical applications, including the latest in embryonic cell development, microfabrication of artificial neural tissue, and microvascular and cardiac tissue engineering. What’s more, this comprehensive resource covers hydrogels for cartilage tissue, bone tissue engineering, kidney replacement therapies, and pulmonary applications. Moreover, the book presents the latest advances in hepatic tissue engineering, immune cell analysis, and the development of engineered skin substitutes.
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Book Abstract:
The application of microfluidics to biotechnology is an exciting new area that has already begun to revolutionize how researchers study and manipulate macromolecules like DNA, proteins and cells in vitro and within living organisms. Presenting an enlightening balance of numerical approaches, theory, and experimental examples, this cutting-edge resource offers keen insight into this burgeoning field. Supported with over 800 equations and more than 340 illustrations, the book provides a detailed look at the mechanical behavior of the different types of micro/nano particles and macromolecules that are used in biotechnology. You gain a solid understanding of microfluidics theory and the mechanics of microflows and microdrops. The book examines the diffusion of species and nanoparticles, including continuous flow and discrete Monte-Carlo methods.
This unique volume describes the transport and dispersion of biochemical species and particles. You learn how to model biochemical reactions, including DNA hybridization and enzymatic reactions. Moreover, the book helps you master the theory, applications, and modeling of magnetic beads behavior and provides an overview of self-assembly and magnetic composite. Other key topics include the electric manipulation of micro/nanoparticles and macromolecules and the experimental aspects of biological macromolecule manipulation.
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Book Abstract:
This forward-looking resource outlines the extraordinary new tools that are becoming available in nanomedicine. The book presents an integrated set of perspectives that describe where we are now and where we should be headed to put nanomedicine devices in to applications as quickly as possible, including consideration of the possible dangers of nanomedicine. Written by some of the most innovative minds in medicine and engineering, this unique volume helps you understand cutting-edge and futuristic areas of research that can have tremendous payoff in terms of improving human health. You find insightful discussions on nanostructured intelligent materials and devices that are considered technically feasible and that have a high potential to produce advances in medicine in the near future.
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Book Abstract:
This first-of-its-kind book presents latest advances in bionanoreactor design and refinement, focusing on the potentially huge applications in cell biology, tissue engineering, and medical diagnostics and therapies. You get full details on the research, practice, synthesis, and characterization of nanoreactors, including 14 actual systems with biomedical relevance explained in full by the pioneers who are developing them.
This trail-blazing volume covers nanoreactor essentials, including a review of synthetic procedures and materials used to develop various nanoreactor configurations. It explores nanoreactor theory and design, highlighting the fundamental differences between molecular events in macroscale and nanoscale reactors. The book offers a clear look at the dominating role of interfaces and how they affect nanoreactor properties and processes. Moreover, it shows how chemical reaction engineering can be applied in analyzing thermodynamics of self-assembly, colloidal stability, reaction kinetics and stochastic effects, and nanoreactor optimization. The book explores integrated nanoreactor systems, covering a theoretical treatment of how nanoreactors can be mobilized inside cells and tissues or as nanostructured films or coatings. Supported by over 100 diagrams and 250 equations, this definitive resource spotlights 14 bionanoreactor systems in development, including organic polymers, vesicles, polymer-stabilized liposomes, artificial protein cages, stem cells, DNA architectures, and others.
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Book Abstract:
This authoritative volume provides an overview of basic and advanced techniques used in quantitative EEG (qEEG) analysis. The book provides a wide range of mathematical tools used in qEEG, from single channel discriptors to the interactions among multi-channel EEG analysis. Moreover, you find coverage of the latest and most popular application in the field, including mental and neurological disease detection/monitoring, physiological and cognitive phenomena research, and fMRI.
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Book Abstract:
Medical automation is an emerging area that is bringing the efficiency tools and methods developed by our most successful corporations to the practice of medicine. Presenting a new systems engineering approach to controlling medical processes, this cutting-edge resource shows you how to reduce time, cost, and errors by at least 50%. The book offers you a solid understanding of medical automation principles and the latest applications in the field. You discover how computers and devices can be used to schedule personnel and services, and help maintain a just-in-time, lean, and more affordable medical services. You learn how to automate your pharmacy and laboratory services for maximum profit and minimum turnaround time. Moreover, this forward-looking book helps you determine how nanotechnology is evolving to solve difficult medical challenges.
This practical volume explains how hospitals are automating their pharmacy supply systems to reduce waiting time for medications and virtually eliminate mis-dosing, delayed dosing, or incorrect dosing of patients. The book also shows you how to automate your clinical laboratory, helping you decrease the need for rapid (or STAT) testing, eliminate the shortage of trained medical technologists, and increase profitability without the need to increase costs.
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Book Abstract:
This groundbreaking volume is the first-ever book to focus on the translational aspect of tissue engineering and regenerative medicine (TE/RM). It offers a unique approach that helps bridge the gap between laboratory discovery and clinical translation/applications. This landmark book identifies the current and upcoming roadblocks in the area of scientific research and technological development of stem cells, tissue engineering, wound healing, and in vivo animal models. You find comprehensive coverage of the technological, regulatory and funding aspects of TE/RM from leading authorities in the field.
The book presents the very latest details in this cutting-edge area, covering multiple tissues, organs and systems. Key topics range from stem cells in regenerative medicine… to common and enabling approaches in TE/RM… to federal funding, industrial approaches, and regulatory mechanisms. This one-of-a-kind resource offers you an interdisciplinary blend of critical knowledge that shows how biology, engineering, and medical research have self-assembled into the growing field of tissue engineering and regenerative medicine.
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Book Abstract:
VLSI (very large scale integration) is the process of creating integrated circuits by combining thousands of transistor based circuits into a single chip. Written by top-notch international experts in industry and academia, this groundbreaking resource presents a comprehensive, state-of-the-art overview of VLSI circuit design for a wide range of applications in biology and medicine.
Supported with over 280 illustrations and over 160 equations, the book offers cutting-edge guidance on designing integrated circuits for wireless biosensing, body implants, biosensing interfaces, and molecular biology. You discover innovative design techniques and novel materials to help you achieve higher levels circuit and system performance. This invaluable volume is essential reading for anyone with a serious interest in circuit design and future biomedical technology, whether you’re a seasoned practitioner or graduate student preparing for work in this challenging field.
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